Outcomes of patients with anemia and renal dysfunction in hospitalized heart failure with preserved ejection fraction (from the CN-HF registry)

Autor:	Xinchun Yang, Kai Hu, Micheal Fu, Yu Song, Junbo Ge, Xuejuan Jin, Yuyuan Fan, Dingli Xu, Wei Dong, Zhenyue Chen, Jun Zhou, Liwen Li, Qiaoqing Zhong, Yanyan Wang, Jingmin Zhou, Juan Cao, Xueting Han, Li Chen, Cn-Hf investigators
Rok vydání:	2019
Předmět:	MRA mineralocorticoid receptor antagonist lcsh:Diseases of the circulatory (Cardiovascular) system medicine.medical_specialty AF atrial fibrillation Anemia LDL low density lipoprotein cholesterol HFpEF heart failure with preserved ejection fraction NT-proBNP N-terminal pro-brain natriuretic peptide Heart failure 030204 cardiovascular system & hematology HF Heart failure Nyha class RD renal dysfunction 03 medical and health sciences 0302 clinical medicine Internal medicine LVEF left ventricular ejection fraction LVDD left ventricular diastolic dimension Medicine In patient CN-HF China National Heart Failure Registration Study 030212 general & internal medicine NYHA New York Heart Association HFrEF heart failure with reduced ejection fraction TC serum total cholesterol ARB angiotensin receptor blockers Original Paper BNP brain natriuretic peptide Ejection fraction TG triglyceride business.industry Proportional hazards model eGFR estimated glomerular filtration rate CRFs case report forms ACEI angiotensin converting enzyme inhibitors medicine.disease HR hazard ratio HDL high density lipoprotein cholesterol CI confidence interval Clinical trial Heart failure with preserved ejection fraction lcsh:RC666-701 Cardiology Renal dysfunction Cardiology and Cardiovascular Medicine business
Zdroj:	International Journal of Cardiology. Heart & Vasculature International Journal of Cardiology: Heart & Vasculature, Vol 25, Iss, Pp-(2019)
ISSN:	2352-9067
DOI:	10.1016/j.ijcha.2019.100415
Popis:	Background: Although a large number of studies on heart failure with reduced ejection fraction (HFrEF) have found that anemia and renal dysfunction (RD) independently predicted poor outcomes, there are still few reports on patients with heart failure with preserved ejection fraction (HFpEF). Methods: Clinical data of HFpEF patients registered in the China National Heart Failure Registration Study (CN-HF) were evaluated and the clinical features of patients with or without anemia/RD were compared to explore the impact of anemia and RD on all-cause mortality and all-cause re-hospitalization. Results: 1604 patients with HFpEF were enrolled, the prevalence of anemia was 51.0%. Although anemia was associated with increased risk of all-cause mortality and all-cause re-hospitalization in univariate COX regression (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8470f4f075f5d6b1958d5c7b8d0b4c https://doi.org/10.1016/j.ijcha.2019.100415 Zobrazit plný text záznamu