Constriction of collateral arteries induced by 'head-up tilt' in patients with occlusive arterial disease of the legs
| Autor: | O Henriksen, K Agerskov, K. H. Tønnesen, Niels A. Lassen |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
medicine.medical_specialty
Physiology Posture Collateral Circulation Arterial Occlusive Diseases Blood Pressure Femoral artery Iliac Artery Physiology (medical) medicine.artery Internal medicine medicine Humans Brachial artery Aged Leg business.industry Blood flow Middle Aged Popliteal artery Femoral Artery medicine.anatomical_structure Blood pressure Regional Blood Flow Vasoconstriction Vascular resistance Cardiology Arterial blood Vascular Resistance Cardiology and Cardiovascular Medicine business |
| Zdroj: | Cardiovascular Research. 15:675-679 |
| ISSN: | 0008-6363 |
| Popis: | The effect of head-up tilt on leg blood flow and segmental arterial blood pressures was studied in 21 patients with occlusion or severe stenosis of the common or superficial femoral artery. Arterial pressure was measured directly in the brachial artery, common femoral artery and popliteal artery. Relative change in blood flow in the leg during tilt was estimated by changes in arterio-venous oxygen differences and by the indicator dilution technique in nine patients. Head-up tilt caused a decrease in leg blood flow of 36% corresponding to an increase in total vascular resistance of 57%. Tilt did not change the pressure gradient from femoral to popliteal artery in the patients with occlusion of the superficial femoral artery, indicating that the flow resistance offered by the collateral arteries had increased. In a bilateral sympathectomised patient the increase in collateral resistance was almost absent indicating that the constriction of the collateral arteries is mainly mediated via sympathetic vasoconstrictor fibres. |
| Databáze: | OpenAIRE |
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