Effect of mycobacterial lipids on surface properties of Curosurf: implications for lung surfactant dysfunction in tuberculosis

Autor:	G. Chimote, Rangan Banerjee
Rok vydání:	2008
Předmět:	Serum Pulmonary and Respiratory Medicine Curosurf (Tm) Sp-B Tuberculosis Physiology Surface Properties Swine Sp-C Atelectasis Microscopy Atomic Force Models Biological Microbiology Mycolic acid Mycobacterium Pulmonary Tuberculosis Mycolic Acid Pulmonary surfactant Adjuvants Immunologic In vivo Spread Monolayers Mechanisms medicine Animals Respiratory system Inhibition chemistry.chemical_classification Cord factor Lung Chemistry Albumin General Neuroscience Proteins Pulmonary Surfactants medicine.disease Lipids Wilhelmy Balance medicine.anatomical_structure Biochemistry Mycolic Acids Cord Factors Lung Surfactant Inhibition Pulmonary Surfactant
Zdroj:	Respiratory physiologyneurobiology. 162(1)
ISSN:	1569-9048
Popis:	In this study, the effect of mycobacterial lipids on the surface activity of lung surfactant was evaluated. Mycolic acid and cord factor, the most abundant surface active lipids of the mycobacterial cell wall when combined with Curosurf (TM) led to alteration of its surface properties. Addition of graded amounts of mycolic acid increased the minimum surface tension of Curosurf (TM) monolayers from
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7eef20735733f9f2c4c779c4ad8d2e https://pubmed.ncbi.nlm.nih.gov/18515195 Zobrazit plný text záznamu Full Text from ScienceDirect