Association between Blood Group and Nonmelanoma Skin Cancers (Basal Cell Carcinoma and Squamous Cell Carcinoma)
| Autor: | Jolanda Kanižaj Rajković, Dijana Celić, Branko Kolarić, Jasna Lipozenčić, Tajana Borlinić, Goran Ferenčak |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Oncology squamous cell carcinoma medicine.medical_specialty BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences Skin Neoplasms Croatia Health Toxicology and Mutagenesis medicine.medical_treatment lcsh:Medicine Logistic regression Article 03 medical and health sciences 0302 clinical medicine nonmelanoma skin cancers basal cell carcinoma Risk Factors Basic research Internal medicine ABO blood group system medicine Humans Basal cell carcinoma Basal cell 030212 general & internal medicine Disease prognosis Aged Aged 80 and over Potential risk business.industry BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti lcsh:R Public Health Environmental and Occupational Health Immunotherapy Middle Aged ABO blood groups medicine.disease Carcinoma Basal Cell 030220 oncology & carcinogenesis Blood Group Antigens Carcinoma Squamous Cell Female business Biomarkers |
| Zdroj: | International Journal of Environmental Research and Public Health Volume 16 Issue 13 International Journal of Environmental Research and Public Health, Vol 16, Iss 13, p 2267 (2019) |
| ISSN: | 1661-7827 |
| Popis: | Background: Development of nonmelanoma skin cancers (NMSCs) has been associated with certain risk factors, but studies of the association between ABO blood group and NMSCs have been rare and inconclusive. The aim of this study was to assess the association of the previously known risk factors and blood group as a new potential risk factor in NMSCs. Methods: The study included 401 patients, 202 men, and 199 women, which included 367 diagnosed cases of basal cell carcinoma and 148 diagnosed cases of squamous cell carcinoma. The control group consisted of 438 subjects, 198 men, and 240 women. A standardized questionnaire adapted for this targeted study was used. The relation between the dependent variable (NMSCs) and independent variables was investigated by logistic regression. Results: Compared to the non AB blood group, the risk of developing NMSCs was significantly higher in the AB blood group (MOR = 2.28 95% CI = 1.41&ndash 3.69). We established a logistic model that could best describe the probability of NMSCs development. Conclusion: Study results are expected to instigate basic research into the role of A and B antigens in normal skin epithelium, NMSCs etiopathogenesis, possible effect on metastatic potential and disease prognosis, potential tumor immunotherapy, and targeted detection and prevention in subjects at an increased risk of NMSCs development. |
| Databáze: | OpenAIRE |
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