Use of chemotherapy as possible means of reducing mortality rate in perforated peptic ulcer

Autor:	John Winslow Hirshfeld, Homer Smathers, Abbott We
Rok vydání:	2010
Předmět:	Chemotherapy medicine.medical_specialty business.industry medicine.medical_treatment Mortality rate Operative mortality Perforation (oil well) General Medicine Disease medicine.disease Surgery Penicillin Streptomycin Peptic ulcer Peptic Ulcer Perforation medicine Humans business medicine.drug
Zdroj:	American journal of surgery. 74(1)
ISSN:	0002-9610
Popis:	1. 1. The operative mortality attending acute perforation of peptic ulcer is in most instances between 15 and 20 per cent. 2. 2. Approximately 80 per cent of the deaths are due to bacterial infection either intraperitoneal or pulmonary. 3. 3. Most of the bacteria involved in these infections are susceptible to penicillin or streptomycin. 4. 4. It is believed that early and intensive treatment with penicillin and streptomycin of all patients with perforated peptic ulcer would reduce the mortality rate of this disease. 5. 5. Chemotherapy should be considered an aid in the treatment of such cases and should not be substituted for careful surgery, or adequate pre- and postoperative care.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac5a441861ac5ce5f19bf153145180da https://pubmed.ncbi.nlm.nih.gov/20249209 Zobrazit plný text záznamu Full Text from ScienceDirect