Comparing perioperative vaginal misoprostol with intraoperative pericervical hemostatic tourniquet in reducing blood loss during abdominal myomectomy: A randomized controlled trial

Autor: Grace G Ezeoke, Muhibat A. Afolabi, Rakiya Saidu, Munirdeen A Ijaiya, Abiodun S Adeniran
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of the Turkish-German Gynecological Association, Vol 20, Iss 1, Pp 23-30 (2019)
Journal of the Turkish German Gynecological Association
ISSN: 1309-0380
1309-0399
Popis: Objective: To compare the effectiveness of perioperative vaginal misoprostol with intraoperative pericervical hemostatic tourniquet in reducing blood loss during abdominal myomectomy. Material and Methods: A randomized controlled trial involving women with uterine leiomyoma who underwent abdominal myomectomy was conducted at a tertiary facility in Nigeria. Participants were recruited after they gave informed consent and randomized into group I (single dose 400 μg vaginal misoprostol one-hour before surgery) and group II (intraoperative pericervical hemostatic tourniquet). Eighty participants (40 in each group) were recruited. Uterine size was measured in centimeters above the pubic symphysis, and blood loss estimation involved direct volume measurement and gravimetric methods. The main outcome measures were intraoperative blood loss, blood transfusion, and recourse to hysterectomy. Ethical approval and trial registration were obtained; the data were analyzed using the SPSS software version 21.0; p
Databáze: OpenAIRE