Possible parathyroid origin of gastrin in a patient with multiple endocrine adenopathy type I
| Autor: | J Cassar, J M Polak, W. M. Cooke |
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| Rok vydání: | 1975 |
| Předmět: |
Male
medicine.medical_specialty Hypercalcaemia endocrine system diseases Adenoma Fluorescent Antibody Technique Endocrine System Diseases Gastroenterology Subtotal Parathyroidectomy Parathyroid Glands Internal medicine Gastrins medicine Humans Multiple endocrine neoplasia Gastrin Gastrinoma Hyperparathyroidism business.industry digestive oral and skin physiology Glucose Tolerance Test Middle Aged medicine.disease Adenoma Islet Cell Hypoglycemia Pancreatic Neoplasms Endocrinology medicine.anatomical_structure Hormones Ectopic Surgery business Pancreas hormones hormone substitutes and hormone antagonists |
| Zdroj: | The British journal of surgery. 62(4) |
| ISSN: | 0007-1323 |
| Popis: | After removal of two large pancreatic insulinomas, although the presenting spontaneous hypoglycaemia was eliminated, severe and persisting haematemesis and melaena supervened with a rise in serum gastrin. The patient had multiple endocrine adenopathy (pituitary, parathyroids and islet cells), but no evidence of a pancreatic gastrin-producing tumour. After emergency gastric operation for the bleeding, the serum gastrin remained high until the hypercalcaemia and hyperparathyroidism had been corrected by subtotal parathyroidectomy. Immunofluorescence studies showed gastrin in the parathyroid tissue. |
| Databáze: | OpenAIRE |
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