Salivary gland ultrasound abnormalities in primary Sjögren's syndrome: consensual US-SG core items definition and reliability

Autor: Aaltje Stel, Alan N. Baer, Sandrine Jousse-Joulin, Vera Milic, Marina Carotti, Joel Fradin, Arjan Vissink, Malin V. Jonsson, Emmanuel Nowak, Alain Saraux, Hendrika Bootsma, John Rout, Alojzija Hočevar, Elke Theander, Valérie Devauchelle-Pensec, Zarrin Alavi, Wan-Fai Ng, Jackie E. Brown, Andrew Carr, Benjamin A Fisher, Chiara Baldini, Simon J. Bowman, Divi Cornec, Nicoletta Luciano
Přispěvatelé: Lymphocyte B et Auto-immunité (LBAI), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Brestois Santé Agro Matière (IBSAM), Université de Brest (UBO), CHRU Brest - Service de Rhumatologie (CHU - BREST - Rhumato), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Centre d'Investigation Clinique (CIC - Brest), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM), Southern Illinois University [Carbondale] (SIU), Dental Radiology - New Castle, Dental Hospital London, Department of Biology, University of Padova, Universita degli Studi di Padova, California Academy of Sciences, Department of Rheumatology (Dep Rheumato - Ljubljana - SLOVENIE), University Medical Centre Slovenia, Research School for Technology Mediated Knowledge Processes [Örebro], Dalarna University, Centro Medico Chirurgico Esculapio (CMC Esculapio - PISE), Centre Medico Chirurgico Esculapio (CMC Esculapio), Institute of Rheumatology, University of Belgrade [Belgrade], Department of Rheumatology (Dep Rheumato - Malmo - SUEDE), Skåne University Hospital, Department of Rheumatology and Clinical Immunology Groningen (Dep Rheum - GRONINGEN), University Medical Center Groningen [Groningen] (UMCG), Department of Oral & Maxillofacial Surgery & Maxillofacial Prosthetics (Dep Oral and Maxillofacial Surgery - GRONINGEN), University Medical Center Groningen and University of Groningen, Rheumatology Unit (Rheum Unit - PISA), University of Pisa - Università di Pisa, Otto-von-Guericke University [Magdeburg] (OVGU), School of Computer Engineering, Nanyang Technological University [Singapour], New Queen Elizabeth Hospital (NQEH - BIRMINGHAM), New Queen Elisabeth Hospital, Translational Immunology Groningen (TRIGR), Personalized Healthcare Technology (PHT)
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: RMD Open : Rheumatic & Musculoskeletal Diseases
RMD Open : Rheumatic & Musculoskeletal Diseases, EULAR ; BMJ, 2017, 3 (1), ⟨10.1136/rmdopen-2016-000364⟩
RMD Open
BMJ Open, 3(1):e000364. BMJ PUBLISHING GROUP
ISSN: 2056-5933
DOI: 10.1136/rmdopen-2016-000364⟩
Popis: ObjectivesUltrasonography (US) is sensitive for detecting echostructural abnormalities of the major salivary glands (SGs) in primary Sjögren’s syndrome (pSS). Our objectives were to define selected US-SG echostructural abnormalities in pSS, set up a preliminary atlas of these definitions and evaluate the consensual definitions reliability in both static and acquisition US-SG images.MethodsInternational experts in SG US in pSS participated in consensus meetings to select and define echostructural abnormalities in pSS. The US reliability of detecting these abnormalities was assessed using a two-step method. First 12 experts used a web-based standardised form to evaluate 60 static US-SG images. Intra observer and interobserver reliabilities were expressed in κ values. Second, five experts, who participated all throughout the study, evaluated US-SG acquisition interobserver reliability in pSS patients.ResultsParotid glands (PGs) and submandibular glands (SMGs) intra observer US reliability on static images was substantial (κ > 0.60) for the two main reliable items (echogenicity and homogeneity) and for the advised pSS diagnosis. PG inter observer reliability was substantial for homogeneity. SMGs interobserver reliability was moderate for homogeneity (κ = 0.46) and fair for echogenicity (κ = 0.38). On acquisition images, PGs interobserver reliability was substantial (κ = 0.62) for echogenicity and moderate (κ = 0.52) for homogeneity. The advised pSS diagnosis reliability was substantial (κ = 0.66). SMGs interobserver reliability was fair (0.20< κ ≤ 0.40) for echogenicity and homogeneity and either slight or poor for all other US core items.ConclusionThis work identified two most reliable US-SG items (echogenicity and homogeneity) to be used by US-SG trained experts. US-PG interobserver reliability result for echogenicity is in line with diagnosis of pSS.
Databáze: OpenAIRE