Respiratory outcomes of late preterm infants of mothers with early and late onset preeclampsia
| Autor: | Belal Alshaikh, Yasser Soliman, Albert Akierman, Kamran Yusuf, Essa Al-Awad, Adel Elsharkawy |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
medicine.medical_specialty
Late preterm infant medicine.medical_treatment Respiratory Tract Diseases Article Cohort Studies 03 medical and health sciences 0302 clinical medicine Pre-Eclampsia Pregnancy 030225 pediatrics Statistical significance Odds Ratio medicine Humans 030212 general & internal medicine Continuous positive airway pressure Mechanical ventilation business.industry Obstetrics Infant Newborn Case-control study Obstetrics and Gynecology Odds ratio medicine.disease Risk factors Outcomes research Case-Control Studies Pediatrics Perinatology and Child Health Female business Infant Premature Cohort study |
| Zdroj: | Journal of Perinatology |
| ISSN: | 1476-5543 0743-8346 |
| Popis: | Objective To study the effect of early and late onset preeclampsia (EOPE, LOPE, respectively) on outcomes of late preterm infants. Study design Cohort study of late preterm infants admitted to a tertiary care NICU from January 2014–July 2015. Outcomes of late preterm infants of EOPE mothers were compared with the next late preterm infant of a LOPE mother and the next two late preterm infants of normotensive non-PE mothers. Primary outcome comprised use of continuous positive airway pressure, mechanical ventilation and/or surfactant in the 24 h after birth. Results Compared to normotensives (n = 131), adjusted odds ratio (AORs) of the primary outcome was higher in the EOPE (n = 64) and LOPE (n = 65) groups but reached statistical significance only in the EOPE group, AORs 12.9, 95% CI 3.5–37 and 2.7, 95% CI 0.95–8.1, respectively. Conclusions Compared to late preterm infants of normotensive and LOPE mothers, infants of mothers with EOPE have significantly higher respiratory morbidity. |
| Databáze: | OpenAIRE |
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