Indoor Allergens and Microbial Bio-Contaminants in Homes of Asthmatic Children in Central Taiwan
| Autor: | Francis Fu-Sheng Wu, Robert Siebers, Mei-Wen Wu, Julian Crane, Chin-Fu Chang, Nevil Pierse, Chi-Ying Chen, Shu-Wen Hsieh |
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| Rok vydání: | 2009 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine Allergy Veterinary medicine beta-Glucans Adolescent Taiwan Cockroach allergen Beds Arthropod Proteins immune system diseases medicine Humans Immunology and Allergy Antigens Dermatophagoides Child Asthma House dust mite biology business.industry Bedding and Linens Dust Asthma symptoms Environmental Exposure Allergens Antigens Plant Immunoglobulin E Contamination medicine.disease biology.organism_classification respiratory tract diseases Endotoxins Asthmatic children Cysteine Endopeptidases Air Pollution Indoor Child Preschool Pediatrics Perinatology and Child Health Immunology Housing Female Bacterial endotoxin business |
| Zdroj: | Journal of Asthma. 46:745-749 |
| ISSN: | 1532-4303 0277-0903 |
| DOI: | 10.1080/02770900903082597 |
| Popis: | Indoor allergens and microbial bio-contaminants play a significant role in asthma symptoms. The aim of the study was to determine levels of house dust mite allergens, bacterial endotoxin, and fungal beta-glucan in homes of 120 asthmatic children in central Taiwan. Dust samples from 120 mattresses (67 double-sided) were analyzed for house dust mite allergens (Der p 1, Der f 1, and Blo t 5), endotoxin, and beta-glucan. Pillows (n = 118) were analyzed for house dust mite allergens only. Kitchen dust samples were analyzed for the cockroach allergen, Bla g 1. Blo t 5 was detected in 9.3% pillows and 82.2% mattresses, Der p 1 in 95.8% pillows and 93.2% mattresses, and Der f 1 in 82.2% pillows and 83.1% mattresses. Geometric mean levels (95% confidence interval) of endotoxin and beta-glucan in mattresses were 108.4 Eu/mg (81.4-144.2) and 25.2 microg/g (22.7-28.0), respectively. House dust mite allergens and endotoxin levels were significantly lower on the bamboo side of 67 mattresses, compared to the inner sprung mattress side. Geometric mean of kitchen Bla g 1 was 0.61 U/g (95% CI: 0.43-0.85). Given the presence of Der p 1, Der f 1 and Blo t 5 in central Taiwan, it is advised to measure allergens of all three house dust mite species to obtain a true index of allergen exposure. Bamboo sides of mattresses had significantly lower house dust mite allergens and endotoxin levels. |
| Databáze: | OpenAIRE |
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