Photoinduced Surface Zwitterionization for Antifouling of Porous Polymer Substrates
| Autor: | Sheng-Han Chen, Kazuhiko Ishihara, Yuuki Inoue, Kyoko Fukazawa |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Materials science
Infrared spectroscopy 02 engineering and technology engineering.material 010402 general chemistry Methacrylate 01 natural sciences chemistry.chemical_compound Adsorption Coating Electrochemistry General Materials Science Spectroscopy chemistry.chemical_classification Surfaces and Interfaces Polymer Polyethylene 021001 nanoscience & nanotechnology Condensed Matter Physics 0104 chemical sciences chemistry Chemical engineering Attenuated total reflection engineering Surface modification 0210 nano-technology |
| Zdroj: | Langmuir : the ACS journal of surfaces and colloids. 35(5) |
| ISSN: | 1520-5827 |
| Popis: | Surface functionalization of polymeric porous substrates is one of the most important requirements to enhance their applications in the biomedical field. In this study, we achieved photoinduced surface modification using a highly efficient reaction of hydrophilic polymers bearing phosphorylcholine groups. Polymers composed of 2-methacryloyloxyethyl phosphorylcholine (MPC) units and 2-( N-ethylanilino)ethyl methacrylate units were synthesized with attention to the polymer architectures. The surface modification of the porous polyethylene (PE) substrates was carried out by the coating of the MPC polymers with a photochemical radical generator, followed by photoirradiation for a few minutes. Surface analysis by attenuated total reflectance Fourier transform IR spectroscopy and X-ray photoelectron spectroscopy indicated that the MPC polymer layer was generated on the PE surface. Cross-sectional confocal microscopy images showed that the MPC polymers were coated on the polymer surface, even inside the porous structure of the PE substrate. After modification, the porous PE substrates showed a significant increase in hydrophilicity and the water-penetration rate through the pores. Furthermore, the amount of protein adsorbed on the PE substrate was reduced significantly by the surface modification. These functionalities were dependent on the MPC polymer architectures. Thus, we concluded that the photoreactive polymer system developed furnished the porous substrates with antifouling properties. |
| Databáze: | OpenAIRE |
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