Zataria multiflora essential oil reduces replication rate of avian influenza virus (H9N2 subtype) in challenged broiler chicks
| Autor: | M Vasfi Marandi, Vahid Karimi, Abbas Barin, A Shayeganmehr, Arash Ghalyanchilangeroudi |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Veterinary medicine viruses animal diseases Respiratory System Biology medicine.disease_cause Virus Replication Antiviral Agents Virus law.invention 03 medical and health sciences Random Allocation 0302 clinical medicine law medicine Amantadine Influenza A Virus H9N2 Subtype Oils Volatile Animals Respiratory system Essential oil Poultry Diseases Lamiaceae Dose-Response Relationship Drug Broiler food and beverages General Medicine Animal Feed Influenza A virus subtype H5N1 Diet Gastrointestinal Tract 030104 developmental biology Viral replication 030220 oncology & carcinogenesis Influenza in Birds Dietary Supplements Animal Science and Zoology medicine.symptom Weight gain Chickens Food Science medicine.drug |
| Zdroj: | British poultry science. 59(4) |
| ISSN: | 1466-1799 |
| Popis: | 1. The effect of Zataria multiflora essential oil on replication rate of the H9N2 virus in target organs was determined by real-time PCR. One-day-old broiler chicks were randomly divided into six groups and were challenged with H9N2 influenza. Two groups received either 20 or 40 µl/kg body weight/day Zataria multiflora essential oils (ZM) seven days before the challenge while two other groups received the essential oil at the same dosage but after H9N2 challenge. One group received 4 mg/kg body weight/day of the anti-viral compound amantadine after challenge and the last group received no treatment and served as the control. 2. Groups that received the ZM, before or after H9N2 challenge, and the amantadine treated group showed reduced viral replication in the respiratory and gastrointestinal tracts compared to the control. Supplementation with ZM improved weight gain and FCR in broilers in comparison with the control. 3. The results showed that ZM had a positive effect on reducing viral replication in both the intestine and trachea of H9N2 influenza infected broiler chickens, that led to milder clinical symptoms and better performance. |
| Databáze: | OpenAIRE |
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