Excessive antibiotics use increased in-hospital mortality in intracerebral hemorrhage patients with stroke-associated infection
| Autor: | Junfeng Shi, Ting-Ting Jiang, Fei Wang, Yinghua Wang, Xiao Wu, Shan-You Hu, Li Wang, Qing Chang, Xinyu Xu, Lijuan Shen |
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| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty medicine.drug_class Antibiotics lcsh:Medicine Infections Severity of Illness Index Article 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine medicine Humans Glasgow Coma Scale 030212 general & internal medicine cardiovascular diseases Hospital Mortality Risk factor lcsh:Science Stroke Aged Cerebral Hemorrhage Intracerebral hemorrhage Multidisciplinary In hospital mortality business.industry Incidence (epidemiology) lcsh:R medicine.disease Prognosis Anti-Bacterial Agents Log-rank test lcsh:Q Female business 030217 neurology & neurosurgery |
| Zdroj: | Scientific Reports Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020) |
| ISSN: | 2045-2322 |
| Popis: | Intracerebral hemorrhage (ICH) is associated with higher incidence of stroke-associated infection (SAI) as well as antibiotic use. However, there were few methods for judging proper antibiotic use in clinical manner. We introduce an index of antibiotic use, called personal antibiotic use density (PAUD), to evaluate the relation between antibiotic use and prognosis of ICH patients with SAI. A total of 162 in 570 ICH patients were observed to diagnose as SAI. Comparing with the survival patients, PAUD, ICH volume, National Institutes of Health Stroke Scale (NIHSS) score and ICH score were significantly higher among those who died, while the Glasgow Coma Scale score and the length of stay were significantly lower (P |
| Databáze: | OpenAIRE |
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