Tonsillar Small Cell Carcinoma: Potential Contribution of Human Papillomavirus
| Autor: | Roger A. Fecher, Brittany A. Leader, Yash Patil, Randall Butler |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Palatine Tonsil
Tonsillar Neoplasms 030209 endocrinology & metabolism Small-cell carcinoma 03 medical and health sciences 0302 clinical medicine Carcinoma medicine Humans Basal cell Carcinoma Small Cell Human papillomavirus Lymph node business.industry Papillomavirus Infections Disease progression Pharyngitis Articles General Medicine Middle Aged medicine.disease 3. Good health medicine.anatomical_structure Lymphatic Metastasis 030220 oncology & carcinogenesis Carcinoma Squamous Cell Disease Progression Cancer research Female Lymph Nodes business |
| Zdroj: | The American Journal of Case Reports |
| ISSN: | 1941-5923 |
| Popis: | Patient: Female, 64 Final Diagnosis: Small cell carcinoma of the tonsil Symptoms: Sore throat Medication: — Clinical Procedure: — Specialty: Oncology Objective: Unknown ethiology Background: Extrapulmonary small cell carcinoma (SmCC) is a relatively rare clinical entity constituting only 2.5–5% of SmCCs. Recently, evidence has emerged that high-risk types of human papillomavirus (HPV) might play an etiologic role in oropharyngeal SmCC, similar to squamous cell carcinoma. Case Report: Here, we present a case of tonsillar SmCC that presented as combined SmCC-squamous cell carcinoma in a cervical lymph node, raising the possibility that the SmCC-component represents disease progression. Conclusions: This case lends further support to the importance of HPV in the development of oropharyngeal SmCC and suggests a mechanism of disease progression. |
| Databáze: | OpenAIRE |
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