Novel anti-malarial hydroxynaphthoquinones with potent broad spectrum anti-protozoal activity

Autor:	N. Mchardy, M. Fry, A. W. Randall, C. D. Ginger, Alan Thomas Hudson, V. S. Latter, B. Hill, R. B. Williams
Rok vydání:	1985
Předmět:	Anti malarial Plasmodium berghei Plasmodium falciparum Antiprotozoal Agents Pharmacology Plasmodium Eimeria Mice Antiprotozoal Agent chemistry.chemical_compound parasitic diseases Theileria medicine Animals Protozoan Infections biology Coccidiosis biology.organism_classification Malaria Theileriasis Toxoplasmosis Animal Infectious Diseases chemistry Toxicity Cattle Animal Science and Zoology Parasitology Hydroxynaphthoquinone Apicomplexa Chickens Toxoplasma Buparvaquone Naphthoquinones medicine.drug
Zdroj:	Parasitology. 90:45-55
ISSN:	1469-8161 0031-1820
DOI:	10.1017/s0031182000049003
Popis:	Novel hydroxynaphthoquinones are reported with outstanding efficacy against Plasmodium, Eimeria and Theileria species. Biochemical evidence is presented for the selective toxicity of these compounds being due to inhibition of parasite respiratory systems.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac24141a56ea977d6aa0fbaa9864bbaf https://doi.org/10.1017/s0031182000049003 Zobrazit plný text záznamu