Racial Disparities in Invasive Streptococcus pneumoniae Infections, 1998-2009
| Autor: | Deborah Aragon, Susan Petit, Ruth Lynfield, Bernard Beall, Billie A. Juni, William Schaffner, Jonathan M. Wortham, Ann Thomas, Arthur Reingold, Elizabeth R. Zell, Lee H. Harrison, Tracy Pondo, Matthew R. Moore, Monica M. Farley, Nancy M. Bennett, Joseph Bareta |
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| Rok vydání: | 2014 |
| Předmět: |
Microbiology (medical)
Pneumococcal disease Population Black People Pneumococcal Infections White People Pneumococcal conjugate vaccine Streptococcus pneumoniae Infections Pneumococcal Vaccines medicine Humans Serotyping education education.field_of_study Vaccines Conjugate business.industry Incidence bacterial infections and mycoses United States Streptococcus pneumoniae Infectious Diseases Epidemiological Monitoring Immunology business Demography medicine.drug |
| Zdroj: | Clinical Infectious Diseases. 58:1250-1257 |
| ISSN: | 1537-6591 1058-4838 |
| DOI: | 10.1093/cid/ciu108 |
| Popis: | Background. Before the introduction of 7-valent pneumococcal conjugate vaccine (PCV7), invasive pneumococcal disease (IPD) rates among blacks were twice the rates in whites. We measured the effects of trends in PCV7type and non-PCV7-type IPD rates on racial disparities in overall IPD and estimated the proportion of IPD caused by serotypes included in the 13-valent pneumococcal conjugate vaccine (PCV13). Methods. We analyzed data from the Active Bacterial Core surveillance system, which performs active, laboratory- and population-based surveillance for IPD for 29.2 million people in the United States, for the period 1998– 2009. For patients with unknown race, we multiplied imputed race to calculate age-, race-, and serotype-specific IPD incidence rates. Results. During 1998–2009, 47 449 IPD cases were identified; race was unknown for 5419 (11%). After multiple imputation, 31 981 (67%) patients were considered white and 13 750 (29%) black. PCV7-type IPD rates in all ages in both races decreased to |
| Databáze: | OpenAIRE |
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