| Autor: |
C. Giannakoylas, Antonia Anogeianaki, George Anogianakis, Efstratios K. Theofilogiannakos, D. Economidis, George Ilonidis, M. Trakatelli |
| Rok vydání: |
2005 |
| Předmět: |
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| Zdroj: |
European Journal of Inflammation, Vol 3 (2005) |
| ISSN: |
2058-7392 |
| Popis: |
We studied systemic reactions associated with immunotherapy in a group of 50 patients with mean age 31.4 years. The group consisted of 36 women and 14 men who followed a three-year immunotherapy treatment with pollen and mite allergen extracts (HAL-Holland Corporation). A total number of 2550 injections were administered. Eight patients developed systemic reactions; 6 had allergic rhinitis and 2 allergic asthma. None developed severe anaphylaxis. Seven of the systemic reactions occurred immediately after injection while one was a late reaction manifested as generalized urticaria, local edema and rubor at the site of the injection. From the 7 patients who showed an immediate reaction, 5 developed generalized urticaria with local edema and rubor at the site of the injection, while 2 presented with bronchial spasm. We did not observe any reaction when the quantity of the extract injection was reduced by 50%. Our study points out that, in the vast majority of cases, immunotherapy is free of severe systemic reactions. Those that occur are associated with the injection of high-density extracts and none of them is severe. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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