Popis: |
The long-term neuropsychiatric consequences of traumatic brain injury are numerous and outstrip their physical counterparts in terms of impact on quality of life and outcomes such as return to work. This chapter will describe the epidemiology, pathology and investigation of brain injury, with a focus on findings that have particular relevance to neuropsychiatric disorders. A discussion of the difficulties in understanding aetiology in the neuropsychiatry of mild traumatic brain injury (mTBI), including postconcussional syndrome, will be undertaken alongside a broader overview of the key predisposing factors for long term psychiatric presentations. A review of the current understanding of post-TBI neuropsychiatric disorder including personality change; cognitive disorders and dementia; aggression; affective and anxiety disorders and psychosis will highlight controversies in the literature. Finally, a summary of pharmacological interventions and practical treatment recommendations based on the best available evidence and clinical utility is described. |