| Autor: |
Lynn McCallum, Robert G. Will, Peter Foley, Neil Turner, Fiona Duncan, Alan J. Jaap, Martin Dennis, Scott Ramsay, Rustam Al-Shahi Salman, Jonathan Rhodes, Steven Makin, Linda Spence, Jon McCafferty, Margarethe van Dijke, Mark Hughes, Kristiina Rannikmae, Tim Russell, Moyra Masson, Billie Morrow, Donald Noble, M O Fitzpatrick, Donald Farquhar, Gillian Mead, Jon Stone, Sarah Chambers, Simon Dummer, Patrick Statham, Sandra Dewar, Johann Selvarajah, Philip White, Robin Sellar, Fiona Hughes, Anne Knox, Simon Hart, Patrick R. Taylor, Ali Harmouche, Alastair Fitzgerald, Colin J Mumford, Michael C Jones, Robin Grant, Belinda Weller, Peter J. D. Andrews, Neo Stavrinos, Andrew J. Farrall, Gillian R. Kerr, Adrian Williams, Alasdair Gray, Fergus N. Doubal, Geraint Roberts, Stuart McClellan, Martin McKechnie, Joanna M. Wardlaw, Sarah L. Keir, Hamza Soleiman, Elizabeth Macdonald, Jasmine Ng, Jerard Ross, Claire Gordon, Siddharthan Chandran, Matthew J. Reed, Mano Shanmuganathan, Neshika Samarasekera, Peter Lange, Ioannis P. Fouyas, Christopher P. Derry, Cathie Sudlow, James M. Wilson, Wendy Young, Judith Anderson, Ralph Bouhaidar, Brian Campbell, Robert Walker, Laura Butler, Matthew Wilson, Yi Ng, Ashok Mathews, Donald Macleod, David Grant, Dilip Patel, Andrew Jamieson, Stanko Yordanov, Dave Caesar, Suvankar Pal, Andrew J Coull, Gareth Clegg, Zoe Morris, Colin B. Josephson, Ashok Jacob, Imran Liaquat, Sam Moultrie, Richard Davenport, Latana Munang, Robin Henderson, Anant Kamat, Simon Leigh-Smith, Susan Duncan, Simon Kerrigan, Graham Mackay, Christine Lerpiniere, Matthew King, Sudipto Ghosh, Fiona Maxwell, Arthur F. Fonville, Patricia Cantley, Alastair Crosswaite, Colin Smith, Trish Elder-Gracie, Elaine Bisset, Joyce Stuart, Helen Spiers, Lynn M Myles, Katrina Dodds, Wendy Morley, Ross Murphy, James W. Ironside, Bethany Threlfall, Mara Sittampalam, Syed Alhadad, Antonia Torgersen, Olayinka A Ogundipe, Conor Maguire, Claire Stirling, William Whiteley, Graham McKillop, Peter Sandercock, Katherine Murray, Frank Morrow, Tim Morse, Iain Todd, David Summers, Alison Pollock, Andrew M. McIntosh, Kate Enright, Rod Gibson, Seona Broadbent, Jane Fothergill, Brian Frier, David Hunt, Paul Brennan, Tracey Millar, Richard Knight, Ian R. Whittle, Andrew Elder, Anne Addison, Peter Keston, Himanshu Shekhar, James W. Dear, Russell Hewett, Henry Simms, Nicola L. Bell, Tom Fitzgerald, Peter Bodkin, Lewis Morrison, Katherine Jackson, Malcolm R. Macleod, Jonathan Carter, Kate Ahmad, Jon Murchison, Helen Cook, Neil Hunter, G. R. Nimmo, Randy Smith, Susan Kealley |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
Stroke. 46:361-368 |
| ISSN: |
1524-4628
0039-2499 |
| DOI: |
10.1161/strokeaha.114.007953 |
| Popis: |
Background and Purpose— The characteristics of intracerebral hemorrhage (ICH) may vary by ICH location because of differences in the distribution of underlying cerebral small vessel diseases. Therefore, we investigated the incidence, characteristics, and outcome of lobar and nonlobar ICH. Methods— In a population-based, prospective inception cohort study of ICH, we used multiple overlapping sources of case ascertainment and follow-up to identify and validate ICH diagnoses in 2010 to 2011 in an adult population of 695 335. Results— There were 128 participants with first-ever primary ICH. The overall incidence of lobar ICH was similar to nonlobar ICH (9.8 [95% confidence interval, 7.7–12.4] versus 8.6 [95% confidence interval, 6.7–11.1] per 100 000 adults/y). At baseline, adults with lobar ICH were more likely to have preceding dementia (21% versus 5%; P =0.01), lower Glasgow Coma Scale scores (median, 13 versus 14; P =0.03), larger ICHs (median, 38 versus 11 mL; P P P =0.02) than those with nonlobar ICH. One-year case fatality was lower after lobar ICH than after nonlobar ICH (adjusted odds ratio for death at 1 year: lobar versus nonlobar ICH 0.21; 95% confidence interval, 0.07–0.63; P =0.006, after adjustment for known predictors of outcome). There were 4 recurrent ICHs, which occurred exclusively in survivors of lobar ICH (annual risk of recurrent ICH after lobar ICH, 11.8%; 95% confidence interval, 4.6%–28.5% versus 0% after nonlobar ICH; log-rank P =0.04). Conclusions— The baseline characteristics and outcome of lobar ICH differ from other locations. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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