Choroidal thickness changes in children with chronic heart failure due to dilated cardiomyopathy
| Autor: | Lidia Ziółkowska, Wojciech Hautz, Krystyna Kanigowska, Klaudia Rakusiewicz |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Cardiomyopathy
Dilated Refractive error medicine.medical_specialty Adolescent medicine.drug_class Dilated cardiomyopathy Spectral domain 030204 cardiovascular system & hematology Ventricular Function Left 03 medical and health sciences 0302 clinical medicine Blood serum Ophthalmology medicine Natriuretic peptide Humans cardiovascular diseases Child Heart Failure Original Paper Ejection fraction Optical coherence tomography business.industry Choroid Clinical course Stroke Volume medicine.disease Chronic heart failure Cross-Sectional Studies Choroidal thickness Heart failure 030221 ophthalmology & optometry sense organs business Tomography Optical Coherence |
| Zdroj: | International Ophthalmology |
| ISSN: | 1573-2630 0165-5701 |
| Popis: | Purpose To evaluate choroidal thickness (CTh) in children with chronic heart failure (CHF) secondary to dilated cardiomyopathy (DCM) using spectral domain optical coherence tomography (SD-OCT) and to compare their values to those of healthy children. Methods Sixty eyes of thirty children (mean age 9.9 ± 3.57 years) with chronic heart failure (left ventricular ejection fraction, LVEF ≤ 55%) due to DCM lasting for over 6 months were prospectively enrolled. The control group consisted of 30 age- (mean age 10.16 ± 3.42 years) and sex-matched healthy children. All participants underwent transthoracic echocardiography with LVEF measured using the Simpson method and had the blood serum level of N-terminal-pro-brain natriuretic peptide marker (NT-proBNP) determined. All children underwent SD-OCT and had subfoveal choroidal thickness (SFCTh) and CTh measured at 1500 µm (μm) nasally, temporally, superiorly and inferiorly from the fovea in both eyes by two investigators. Results CTh at all locations was statistically significantly lower in children with DCM compared to the control group. Mean CTh in the group with CHF compared to the control group were (304.03 vs. 369.72 μm, p p p p p p p Conclusion Patients with CHF due to DCM had a thinner CTh at all measured locations. The results of our research indicate that CHF affects CTh and this parameter may be very helpful in monitoring the clinical course of the disease in children with DCM. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink