Clinical Characteristics of Patients with Diabetic Nephropathy on Maintenance Hemodialysis
Autor: | Hu Chen, De-Guang Wang, Gui-Ling Liu, Juan Wang, Heng-Jie He, Li Hao, Sen Zhang, Liang Yuan |
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Rok vydání: | 2016 |
Předmět: |
Male
China medicine.medical_specialty Cross-sectional study Cardiovascular Complication medicine.medical_treatment 030232 urology & nephrology Vascular access lcsh:Medicine Coronary Disease 030204 cardiovascular system & hematology Diabetic nephropathy 03 medical and health sciences 0302 clinical medicine Diabetic Nephropathy Renal Dialysis Internal medicine medicine Humans Diabetic Nephropathies Aged Calcium Hemodialysis Parathyroid Hormone Phosphorus business.industry Incidence (epidemiology) lcsh:R Eastern china General Medicine Maintenance hemodialysis Middle Aged medicine.disease Surgery Cross-Sectional Studies Hypertension Original Article Female Intracranial Thrombosis business |
Zdroj: | Chinese Medical Journal, Vol 129, Iss 11, Pp 1291-1297 (2016) Chinese Medical Journal |
ISSN: | 0366-6999 |
Popis: | Background: The incidence of diabetic nephropathy (DN) increases year by year. However, clinical characteristics of DN patients on maintenance hemodialysis (MHD) were rarely reported in China. The purpose of this study was to examine the clinical characteristics of the DN patients on MHD in Anhui Province, Eastern China. Methods: The clinical data of MHD patients in the hemodialysis centers of 26 hospitals in Anhui Province from January 1, 2014, to March 31, 2014, were examined. The differences between DN patients and non-DN patients were compared regarding vascular access, nutritional status, mineral and bone disorder, and other indexes. Results: Among the selected 2768 adult MHD patients, 427 had DN. The incidence of hypertension, coronary heart disease, and cerebral thrombus in DN patients was 94.1%, 21.5%, and 15.0%, respectively, which were higher than those in non-DN patients (P < 0.001). Category of vascular access for hemodialysis in DN patients was arteriovenous fistula (AVF) (87.4% [373/427]) and tunneled cuffed catheter (TCC) (11.2% [48/427]). The percentage of AVF was significantly lower than that of non-DN patients (P < 0.001), and percentage of TCC was significantly higher than that of non-DN patients (P < 0.001). Hemoglobin achievement rate in DN patients was 32.0%. The incidence of hypoalbuminemia was 24.7%, significantly higher than that in non-DN patients (P < 0.001). The achievement rate of the target range in mineral values was 55.9% in corrected serum calcium level, 30.1% in serum phosphorus level, and 49.3% in intact parathyroid hormone (iPTH) level in DN patients. Compared with non-DN patients, the achievement rate of serum phosphorus was significantly higher in DN patients. Conclusions: DN patients on MHD in Anhui province exhibited different clinical characteristics compared to non-DN hemodialysis patients. They presented higher percentage in TCC use and cardiovascular complication, lower serum albumin and iPTH levels than those in non-DN patients. |
Databáze: | OpenAIRE |
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