Modification of Physical Properties of Certain Antitussive and Antihistaminic Agents by Formation of N-Cyclohexylsulfamate Salts

Autor:	James A. Campbell, James G. Slater
Rok vydání:	1962
Předmět:	Taste Chemistry Pharmaceutical Science Dextromethorphan Accelerated aging Physical Phenomena Antitussive Agents Antitussive Agent Anti-Allergic Agents Histamine H1 Antagonists medicine Organic chemistry Salts Solubility medicine.drug
Zdroj:	Journal of Pharmaceutical Sciences. 51:931-934
ISSN:	0022-3549
DOI:	10.1002/jps.2600511005
Popis:	The N-cyclohexylsulfamic acid salts of four well known therapeutic agents were prepared. Salts of two of the compounds, dextromethorphan and chlorpheniramine, were found to have greatly improved taste and increased solubility. Accelerated aging studies indicate good stability.
Databáze:	OpenAIRE
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