Effect of Regional Upper Septal Hypertrophy on Echocardiographic Assessment of Left Ventricular Mass and Remodeling in Aortic Stenosis
| Autor: | Ezequiel Guzzetti, Mylène Shen, Julio Garcia, Eric Larose, Marie Arsenault, Florent Le Ven, Marie-Annick Clavel, Lionel Tastet, Jérémy Bernard, Elisabeth Bédard, Mohamed-Salah Annabi, Philippe Pibarot, Romain Capoulade |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Heart Ventricles 030204 cardiovascular system & hematology Doppler echocardiography 030218 nuclear medicine & medical imaging Septal wall Left ventricular mass 03 medical and health sciences 0302 clinical medicine Internal medicine Septal hypertrophy Humans Medicine Radiology Nuclear Medicine and imaging In patient medicine.diagnostic_test business.industry Reproducibility of Results Magnetic resonance imaging Mean age Aortic Valve Stenosis Hypertrophy Middle Aged medicine.disease Stenosis Echocardiography Cardiology Female Hypertrophy Left Ventricular Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of the American Society of Echocardiography. 34:62-71 |
| ISSN: | 0894-7317 |
| Popis: | BACKGROUND Transthoracic echocardiography (TTE) is the reference method for evaluation of aortic stenosis (AS), and it is extensively used to quantitate left ventricular (LV) mass and volumes. Regional upper septal hypertrophy (USH) or septal bulge is a frequent finding in patients with AS and may lead to overestimation of LV mass when using linear measurements. The objective of this study was to compare estimates of LV mass obtained by two-dimensional transthoracic echocardiographic LV dimensions measured at different levels of the LV cavity with those obtained by cardiovascular magnetic resonance (CMR). METHODS One hundred six patients (mean age, 63 ± 15 years; 68% men) with AS were included in this subanalysis of the PROGRESSA study. Two-dimensional transthoracic echocardiographic measurements of LV dimensions were obtained at the basal level (BL; as recommended in guidelines), immediately below the septal bulge (BSB), and at a midventricular level (ML). Regional USH was defined as a basal interventricular septal thickness ≥ 13 mm and >1.3 times the thickness of the septal wall at the ML. Agreement between transthoracic echocardiographic and CMR measures was evaluated using Bland-Altman analysis. RESULTS The distribution of AS severity was mild in 23%, moderate in 57%, and severe in 20% of patients. Regional USH was present in 28 patients (26%). In the whole cohort, two-dimensional TTE overestimated LV mass (bias: BL, +60 ± 31 g; BSB, +59 ± 32 g; ML, +54 ± 32 g; P = .02). The biplane Simpson method slightly but significantly underestimated LV end-diastolic volume (bias -10 ± 20 mL, P |
| Databáze: | OpenAIRE |
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