Physical Activity Monitoring: A Responsive and Meaningful Patient-Centered Outcome for Surgery, Chemotherapy, or Radiotherapy?
| Autor: | P. O. Hendry, Max Dahele, Angela Scott, Jacob Stensteth, Tom Preston, Florian Strasser, Eduardo Ferriolli, Kenneth C. H. Fearon, Carolyn A. Greig, Marie Fallon, Lucy Wall, Richard J E Skipworth |
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| Přispěvatelé: | Radiation Oncology, CCA - Quality of life |
| Rok vydání: | 2012 |
| Předmět: |
Male
medicine.medical_specialty Activities of daily living medicine.medical_treatment Context (language use) Motor Activity Sitting Sensitivity and Specificity Quality of life Neoplasms Patient-Centered Care Activities of Daily Living Outcome Assessment Health Care medicine Humans Gastrointestinal cancer General Nursing Aged business.industry Reproducibility of Results Cancer Middle Aged medicine.disease Actigraphy humanities Surgery Clinical trial Radiation therapy Treatment Outcome Anesthesiology and Pain Medicine Physical therapy SENSIBILIDADE E ESPECIFICIDADE Female Neurology (clinical) business |
| Zdroj: | Journal of Pain and Symptom Management, 43(6), 1025-1035. Elsevier Inc. Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP Ferriolli, E, Skipworth, R J E, Hendry, P, Scott, A, Stensteth, J, Dahele, M R, Wall, L, Greig, C, Fallon, M, Strasser, F, Preston, T & Fearon, K C H 2012, ' Physical Activity Monitoring: A Responsive and Meaningful Patient-Centered Outcome for Surgery, Chemotherapy, or Radiotherapy? ', Journal of Pain and Symptom Management, vol. 43, no. 6, pp. 1025-1035 . https://doi.org/10.1016/j.jpainsymman.2011.06.013 |
| ISSN: | 0885-3924 |
| DOI: | 10.1016/j.jpainsymman.2011.06.013 |
| Popis: | Context In surgical and clinical oncology, there is a growing need for patient-centered outcomes that are responsive, meaningful, and fit for purpose. Objectives The aim of this study was to validate physical activity (PA) monitoring as a responsive outcome measure at different stages of disease and treatment, by verifying correlations between PA, performance score, and quality of life (QoL). Methods Daily life PA of 162 cancer patients, monitored by a device that records time sitting/lying, time standing, time walking, number of steps taken, and walking cadence, was compared with 20 healthy volunteers. In a subgroup of patients, functional status and QoL were assessed using the World Health Organization/Eastern Cooperative Oncology Group and the Karnofsky Performance Status scores and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 (EORTC QLQ-C30) questionnaire. Results The PA of patients with resectable gastrointestinal cancer did not differ significantly from controls. In contrast, patients with advanced cancer took 45% fewer steps and spent an extra 2.8 hours/day lying/sitting (P=0.001). Patients undergoing neoadjuvant chemotherapy and surgery (5–6 weeks after operation) experienced a similar reduction in PA. There were significant correlations between PA and the physical and role domains as well as fatigue subscale of the EORTC QLQ-C30 scale. Conclusion Objective PA scores correlate significantly with disease stage, functional status, and QoL of patients with cancer. Therefore, activity monitoring can make meaningful objective estimates of patient function in response to cancer and its treatment and may provide surrogate outcomes of QoL. |
| Databáze: | OpenAIRE |
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