Trajectories of Treatment Response and Nonresponse in Youth at High Risk for Suicide

Autor: Michele S. Berk, Robert Gallop, Joan R. Asarnow, Molly Adrian, Claudia Avina, Jennifer L. Hughes, Kathryn E. Korslund, Elizabeth McCauley
Rok vydání: 2022
Předmět:
Zdroj: Journal of the American Academy of Child & Adolescent Psychiatry. 61:1119-1130
ISSN: 0890-8567
DOI: 10.1016/j.jaac.2022.01.010
Popis: To examine trajectories of treatment response in suicidal youth who participated in a randomized controlled trial comparing dialectical behavior therapy (DBT) and individual and group supportive therapy.Using latent class analysis across both treatment conditions, secondary analyses were conducted of data from a multisite randomized controlled trial comprising 173 youths ages 12-18 with repetitive self-harm (SH) (including ≥1 lifetime suicide attempts) and elevated suicidal ideation (SI). The sample was 95% female, 56.4% White, and 27.49% Latina. Participants received 6 months of DBT or individual and group supportive therapy and 6 months of follow-up. Primary outcomes were SH and SI.Of the sample, 63% and 74% were members of latent classes that showed improvement in SI and SH, respectively; 13% were total nonresponders, with no improvement in SI or SH. SH nonresponse emerged at the midpoint of treatment (3 months), with nonresponders showing a sharp increase in SH over the remainder of treatment and follow-up. Youth receiving DBT were significantly more likely to be an SH responder vs nonresponder than youths in individual and group supportive therapy (ꭓThis is the first study to identify trajectories of both SI and SH response to treatment in a sample of adolescents at risk of suicide. Results may inform personalized treatment approaches.Collaborative Adolescent Research on Emotions and Suicide (CARES); https://www.gov/; NCT01528020.
Databáze: OpenAIRE