Effect of chewing Qat on mucosal histology and prevalence of Helicobacter pylori in the oesophagus, stomach and duodenum of Yemeni patients
| Autor: | N. Zureikat, Sami Shousha, A. M. El-Sherif, A. El-Guneid, I M Murray-Lyon |
|---|---|
| Rok vydání: | 1991 |
| Předmět: |
Male
medicine.medical_specialty Yemen Histology Duodenum Colony Count Microbial Gastroenterology Pathology and Forensic Medicine Esophagus Internal medicine Metaplasia Epidemiology Humans Medicine Dyspepsia Mastication Helicobacter pylori biology business.industry Stomach Incidence (epidemiology) Smoking digestive oral and skin physiology Intestinal metaplasia General Medicine Plants biology.organism_classification medicine.disease digestive system diseases Microscopy Electron medicine.anatomical_structure Gastric Mucosa Duodenal Ulcer Female medicine.symptom business |
| Zdroj: | Histopathology. 19:437-444 |
| ISSN: | 1365-2559 0309-0167 |
| DOI: | 10.1111/j.1365-2559.1991.tb00234.x |
| Popis: | This investigation was aimed at assessing whether the Yemeni habit of chewing Qat on a regular basis had a significant effect on the upper alimentary tract. Seventy patients with dyspepsia attending Al-Thawra Hospital in Taiz, Yemen Republic were examined by endoscopy. Biopsies were taken from the oesophagus, stomach and duodenum. The patients included 28 who gave a history of daily Qat intake, 21 with less frequent intake and 21 who took none. The only statistically significant finding associated with daily Qat intake was a higher prevalence of duodenal ulcer, particularly in females. However, a strong association was also found between heavy smoking and ulcer, with most ulcer patients who chewed Qat daily being heavy smokers. Chewing Qat was not associated with a higher prevalence of oesophageal dysplasia, making it unlikely to be the cause of the perceived high incidence of oesophageal carcinoma in Yemen. There was a high prevalence of gastric H. pylori colonization (93%) and columnar-lined lower end of oesophagus (18%), as well as low prevalence of intestinal metaplasia of stomach (4%); this was not, however, related to chewing Qat. Further epidemiological and histological studies are needed to assess the significance of these findings in relation to the incidence of oesophageal and gastric carcinoma in Yemen. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text