The role of low keV virtual monochromatic imaging in increasing the conspicuity of primary breast cancer in dual-energy spectral thoracic CT examination for staging purposes
| Autor: | Nurgül Orhan Metin, Filiz Taşçı, Sibel Kul, Yavuz Metin, Oguzhan Ozdemir |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Lung Neoplasms Radiography Breast Neoplasms Radiography Dual-Energy Scanned Projection Breast cancer medicine Thoracic ct Humans Radiology Nuclear Medicine and imaging Aged Neoplasm Staging Retrospective Studies Aged 80 and over Radiological and Ultrasound Technology Dual energy business.industry Reproducibility of Results General Medicine Middle Aged medicine.disease Radiographic Image Interpretation Computer-Assisted Neoplasm staging Female Tomography Monochromatic color Primary breast cancer business Nuclear medicine Tomography X-Ray Computed |
| Zdroj: | Acta radiologica (Stockholm, Sweden : 1987). 61(2) |
| ISSN: | 1600-0455 |
| Popis: | Background The additive value of dual-energy spectral computerized tomography (DESCT) in breast cancer imaging is still unknown. Purpose To investigate the role of DESCT in improving the conspicuity of primary breast cancer. Material and Methods Twenty-nine patients who were histopathologically diagnosed with breast cancer and underwent DESCT for staging of lung metastasis were evaluated retrospectively. The visual conspicuity of breast cancer was scored by two readers separately in reconstructed virtual monochromatic images obtained at 40, 60, 80, and 100 keV. A circular region of interest slightly smaller than the maximum contrasted portion of the primary breast cancer was manually placed. Iodine enhancement (HU) and iodine content (mg/mL) values of tumor, normal breast tissue and pectoral muscle, and contrast-to-noise values of images at four different energy levels were calculated. Results The lesion conspicuity score peaked at 40-keV series for both readers and was significantly higher than those at other energy levels (all P Conclusion The conspicuity of primary breast cancer was significantly higher in low keV virtual monochromatic images obtained by DESCT. This gives us hope that DESCT may play an effective role in detecting incidental breast lesions. It also raises the question of whether quantitative values obtained by DESCT can be used for characterization of primary breast lesion. |
| Databáze: | OpenAIRE |
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