Rapid appearance of severe mitral regurgitation under high-dosage corticosteroid therapy in a patient with systemic lupus erythematosus
| Autor: | H.-G. Sieberth, F. A. Schöndube, N. Maurin, Harald Lethen, U. Zunker, R. Hoffman |
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| Rok vydání: | 1994 |
| Předmět: |
Adult
medicine.medical_specialty Systemic disease Time Factors medicine.drug_class medicine.medical_treatment Prednisolone macromolecular substances immune system diseases Mitral valve Medicine Humans Lupus Erythematosus Systemic skin and connective tissue diseases Adverse effect Chemotherapy Mitral regurgitation Lupus erythematosus business.industry Mitral Valve Insufficiency medicine.disease Connective tissue disease Echocardiography Doppler Surgery medicine.anatomical_structure Heart Valve Prosthesis Corticosteroid Mitral Valve Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | European heart journal. 15(1) |
| ISSN: | 0195-668X |
| Popis: | Survival of patients with systemic lupus erythematosus has increased with corticosteroid therapy. However, adverse effects of corticosteroid therapy on cardiovascular structures, such as scarring and shrinking of affected valves, are not well known. We report the case of a 19-year-old patient who developed severe mitral insufficiency within a few weeks after high-dosage corticosteroid therapy had been instituted for an acute relapse of systemic lupus erythematosus. The rapid development of severe mitral regurgitation was documented by sequential colour Doppler echocardiography. |
| Databáze: | OpenAIRE |
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