The diagnostic usefulness of the combined COMPASS 31 questionnaire and electrochemical skin conductance for diabetic cardiovascular autonomic neuropathy and diabetic polyneuropathy
| Autor: | Valentina Izzo, Chiara Maria Assunta Cefalo, Vincenza Spallone, Giorgio Lombardo, Valentina Frattina, Mariagrazia Campo, Carla Greco, Davide Lauro, Cinzia D’Amato |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty animal structures diagnosis Sensitivity and Specificity Severity of Illness Index Settore MED/13 Diabetic Neuropathies Diabetic polyneuropathy Internal medicine Diabetes mellitus Compass medicine Humans reproductive and urinary physiology Aged diabetes business.industry General Neuroscience sudomotor function fungi food and beverages Galvanic Skin Response Middle Aged medicine.disease Autonomic Nervous System Diseases Weighted score embryonic structures Cardiology Autonomic symptoms symptoms Female neuropathy Neurology (clinical) Abnormality Skin conductance Autonomic neuropathy business |
| Popis: | The study investigated the diagnostic performance for diabetic cardiovascular autonomic neuropathy (CAN) and diabetic polyneuropathy (DPN) of the combined use of composite autonomic symptom score (COMPASS) 31, validated questionnaire for autonomic symptoms of CAN, and electrochemical skin conductance (ESC), proposed for detecting DPN and CAN. One-hundred and two participants with diabetes (age 57 ± 14 years, duration 17 ± 13 years) completed the COMPASS 31 before assessing cardiovascular reflex tests (CARTs), neuropathic symptoms, signs, vibratory perception threshold (VPT), thermal thresholds (TT), and ESC using Sudoscan. Two patterns were evaluated: (a) the combined abnormalities in both tests (COMPASS 31+ESC), and (b) the abnormality in COMPASS 31 and/or ESC (COMPASS 31 and/or ESC). CAN (≥1 abnormal CART) and confirmed CAN (≥2 abnormal CARTs) were present in 28.1% and 12.5%, DPN (two abnormalities among symptoms, signs, VPT, and TT) in 52%, abnormal COMPASS 31 (total weighted score >16.44) in 48% and abnormal ESC (hands ESC |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|