A potential risk of overestimating apparent diffusion coefficient in parotid glands
| Autor: | Guo-Shu Huang, Hsian-He Hsu, Yi-Hsiung Lee, K Hsu, Yi-Jui Liu, Ta-Wei Chiou, Hing-Chiu Chang, Teng-Yi Huang, Chun-Jung Juan, Hui-Chu Chiu, Chih-Wei Wang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Risk medicine.medical_specialty lcsh:Medicine Nuclear magnetic resonance stomatognathic system Image Processing Computer-Assisted Humans Parotid Gland Medicine Effective diffusion coefficient cardiovascular diseases Diffusion (business) lcsh:Science Transient signal Multidisciplinary medicine.diagnostic_test Echo-Planar Imaging business.industry Potential risk lcsh:R Single shot Magnetic resonance imaging Middle Aged Parotid gland Radiography body regions Diffusion Magnetic Resonance Imaging medicine.anatomical_structure Head and Neck Neoplasms Case-Control Studies Female lcsh:Q Radiology business Research Article Diffusion MRI |
| Zdroj: | PLoS ONE, Vol 10, Iss 4, p e0124118 (2015) PLoS ONE |
| ISSN: | 1932-6203 |
| Popis: | Objectives: To investigate transient signal loss on diffusion weighted images (DWI) and overestimation of apparent diffusion coefficient (ADC) in parotid glands using single shot echoplanar DWI (EPDWI). Materials and Methods: This study enrolled 6 healthy subjects and 7 patients receiving radiotherapy. All participants received dynamic EPDWI with a total of 8 repetitions. Imaging quality of DWI was evaluated. Probability of severe overestimation of ADC (soADC), defined by an ADC ratio more than 1.2, was calculated. Error on T2WI, DWI, and ADC was computed. Statistical analysis included paired Student t testing and Mann-Whitney U test. A P value less than 0.05 was considered statistically significant. Results: Transient signal loss was visually detected on some excitations of DWI but not on T2WI or mean DWI. soADC occurred randomly among 8 excitations and 3 directions of diffusion encoding gradients. Probability of soADC was significantly higher in radiotherapy group (42.86%) than in healthy group (24.39%). The mean error percentage decreased as the number of excitations increased on all images, and, it was smallest on T2WI, followed by DWI and ADC in an increasing order. Conclusions: Transient signal loss on DWI was successfully detected by dynamic EPDWI. The signal loss on DWI and overestimation of ADC could be partially remedied by increasing the number of excitations. © 2015 Liu et al. published_or_final_version |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|