Improved detection of breast cancer nuclei using modular neural networks

Autor: Schnorrenberg, F., Tsapatsoulis, Nicolas, Pattichis, Constantinos S., Schizas, Christos N., Kollias, S., Vassiliou, M., Adamou, Adamos K., Kyriacou, Kyriacos C.
Přispěvatelé: Schizas, Christos N. [0000-0001-6548-4980], Pattichis, Constantinos S. [0000-0003-1271-8151], Tsapatsoulis, Nicolas [0000-0002-6739-8602]
Rok vydání: 2000
Předmět:
Pathology
Biomedical
Biopsy
receptive field
Modular Neural Network
progesterone receptor
Image analysis
Pattern Recognition
Automated

Immunoenzyme Techniques
immunocytochemistry
cancer diagnosis
Image Processing
Computer-Assisted

Coloring Agents
Hematoxylin
Breast cancer nuclei
Biopsy analysis support systems (BASS)
Artificial neural network
article
General Medicine
Computer simulation
Immunohistochemistry
Computer aided diagnosis
Oncology
Receptors
Estrogen

histopathology
Engineering and Technology
Female
Medical imaging
optical density
Receptors
Progesterone

Algorithms
estrogen receptor
medicine.medical_specialty
Biomedical Engineering
Breast Neoplasms
Biology
Matrix algebra
breast cancer
Breast cancer
medicine
Humans
human
Cellular biophysics
Cell Nucleus
algorithm
Feedforward neural networks
business.industry
Reproducibility of Results
Cancer
Neural Networks (Computer)
Modular neural networks
Modular design
medicine.disease
Modular neural network
human tissue
ROC Curve
Neural Networks
Computer

business
artificial neural network
Zdroj: Europe PubMed Central
IEEE Engineering in Medicine and Biology Magazine
IEEE Eng.Med.Biol.Mag.
ISSN: 0739-5175
DOI: 10.1109/51.816244
Popis: Discusses the analysis of nuclei in histopathological sections with a system that closely simulates human experts. The evaluation of immunocytochemically stained histopathological sections presents a complex problem due to many variations that are inherent in the methodology. In this respect, many aspects of immunocytochemistry remain unresolved, despite the fact that results may carry important diagnostic, prognostic, and therapeutic information. In this article, a modular neural network-based approach to the detection and classification of breast cancer nuclei stained for steroid receptors in histopathological sections is described and evaluated.
Databáze: OpenAIRE