Diffraction-Unlimited Photomanipulation at the Plasma Membrane via Specifically Targeted Upconversion Nanoparticles

Autor: Christoph Drees, Philipp Rühl, Stefan H. Heinemann, Jacqueline Czerny, Janosch Bajorath, Gemini Chandra, Markus Haase, Jacob Piehler
Rok vydání: 2021
Předmět:
Zdroj: Nano letters. 21(19)
ISSN: 1530-6992
Popis: Engineered UCNP are used to trigger rapid photoconversion of the fluorescent protein Dendra2 with nanoscopic precision and over longer distances in mammalian cells. By exploiting the synergy of high-level thulium doping with core-shell design and elevated excitation intensities, intense UCNP emission is achieved, allowing fast photoconversion of Dendra2 with
Databáze: OpenAIRE