Diffraction-Unlimited Photomanipulation at the Plasma Membrane via Specifically Targeted Upconversion Nanoparticles
Autor: | Christoph Drees, Philipp Rühl, Stefan H. Heinemann, Jacqueline Czerny, Janosch Bajorath, Gemini Chandra, Markus Haase, Jacob Piehler |
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Rok vydání: | 2021 |
Předmět: |
Chemistry
Endosome Mechanical Engineering Cell Membrane Green Fluorescent Proteins Nanoparticle Bioengineering General Chemistry Condensed Matter Physics Photon upconversion Green fluorescent protein Surface coating Membrane Biophysics Surface modification Animals Nanoparticles General Materials Science Intracellular |
Zdroj: | Nano letters. 21(19) |
ISSN: | 1530-6992 |
Popis: | Engineered UCNP are used to trigger rapid photoconversion of the fluorescent protein Dendra2 with nanoscopic precision and over longer distances in mammalian cells. By exploiting the synergy of high-level thulium doping with core-shell design and elevated excitation intensities, intense UCNP emission is achieved, allowing fast photoconversion of Dendra2 with |
Databáze: | OpenAIRE |
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