Clinical prediction model to aid emergency doctors managing febrile children at risk of serious bacterial infections: diagnostic study
Autor: | Rianne Oostenbrink, Mirjam van Veen, Ruud G. Nijman, Alfred H J van Meurs, Henriëtte A. Moll, Matthew Thompson, Yvonne Vergouwe, Johan van der Lei, Ewout W. Steyerberg |
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Přispěvatelé: | Pediatrics, Public Health, Medical Informatics |
Rok vydání: | 2013 |
Předmět: |
Male
medicine.medical_specialty Adolescent Fever Risk Assessment Severity of Illness Index Risk Factors Severity of illness medicine Humans Prospective Studies Intensive care medicine Prospective cohort study Child Models Statistical business.industry Research External validation Infant General Medicine Emergency department Bacterial Infections medicine.disease Prognosis Confidence interval Pneumonia C-Reactive Protein Multicenter study Child Preschool Female Emergencies Risk assessment business Emergency Service Hospital |
Zdroj: | BMJ Open Gastroenterology, 346. BMJ Publishing Group The BMJ |
ISSN: | 2054-4774 |
Popis: | OBJECTIVE: To derive, cross validate, and externally validate a clinical prediction model that assesses the risks of different serious bacterial infections in children with fever at the emergency department. DESIGN: Prospective observational diagnostic study. SETTING: Three paediatric emergency care units: two in the Netherlands and one in the United Kingdom. PARTICIPANTS: Children with fever, aged 1 month to 15 years, at three paediatric emergency care units: Rotterdam (n=1750) and the Hague (n=967), the Netherlands, and Coventry (n=487), United Kingdom. A prediction model was constructed using multivariable polytomous logistic regression analysis and included the predefined predictor variables age, duration of fever, tachycardia, temperature, tachypnoea, ill appearance, chest wall retractions, prolonged capillary refill time (>3 seconds), oxygen saturation |
Databáze: | OpenAIRE |
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