Clinical prediction model to aid emergency doctors managing febrile children at risk of serious bacterial infections: diagnostic study

Autor: Rianne Oostenbrink, Mirjam van Veen, Ruud G. Nijman, Alfred H J van Meurs, Henriëtte A. Moll, Matthew Thompson, Yvonne Vergouwe, Johan van der Lei, Ewout W. Steyerberg
Přispěvatelé: Pediatrics, Public Health, Medical Informatics
Rok vydání: 2013
Předmět:
Zdroj: BMJ Open Gastroenterology, 346. BMJ Publishing Group
The BMJ
ISSN: 2054-4774
Popis: OBJECTIVE: To derive, cross validate, and externally validate a clinical prediction model that assesses the risks of different serious bacterial infections in children with fever at the emergency department. DESIGN: Prospective observational diagnostic study. SETTING: Three paediatric emergency care units: two in the Netherlands and one in the United Kingdom. PARTICIPANTS: Children with fever, aged 1 month to 15 years, at three paediatric emergency care units: Rotterdam (n=1750) and the Hague (n=967), the Netherlands, and Coventry (n=487), United Kingdom. A prediction model was constructed using multivariable polytomous logistic regression analysis and included the predefined predictor variables age, duration of fever, tachycardia, temperature, tachypnoea, ill appearance, chest wall retractions, prolonged capillary refill time (>3 seconds), oxygen saturation
Databáze: OpenAIRE