The validity of the static-charge-sensitive bed in the detection of fentanyl-induced respiratory depression
| Autor: | Olli Kirvelä, Kari Leino, Riikka S.K. Takala, E M Nikkola, M A O Salonen |
|---|---|
| Rok vydání: | 2004 |
| Předmět: |
Adult
Male Respiratory rate Hemodynamics Blood Pressure Beds Respiratory monitoring Online Systems Fentanyl Oxygen Consumption Humans Medicine Plethysmograph Analysis of Variance business.industry Respiration Reproducibility of Results Repeated measures design General Medicine Oxygenation Carbon Dioxide Analgesics Opioid Oxygen Plethysmography Anesthesiology and Pain Medicine Oxyhemoglobins Anesthesia Breathing Respiratory Insufficiency business medicine.drug |
| Zdroj: | Acta Anaesthesiologica Scandinavica. 48:371-376 |
| ISSN: | 1399-6576 0001-5172 |
| DOI: | 10.1111/j.0001-5172.2004.0291.x |
| Popis: | Background: Only a few methods for the measurement of breathing are non-invasive and do not interfere with measured parameters. The static-charge-sensitive bed (SCSB) could be such a monitor. The aim of this study was to evaluate the validity of the SCSB compared with the respiratory inductive plethysmograph (RIP) using a fentanyl-induced respiratory depression model. Methods: Eight healthy male volunteers were infused with intravenous (i.v.) fentanyl (15 µg/kg/h) until a decrease in SpO2 below 90% for 1 min emerged. Breathing was continuously and simultaneously measured with SCSB and RIP. Oxygenation, hemodynamics, arterial blood gas analysis, and subjective opioid-related effects were monitored. Fentanyl concentration was measured from an arterial blood sample. The respiratory rate data of the SCSB (automated analysis and manual calculation) were compared with the corresponding RIP data, using analysis of variance for repeated measures. The validity of the SCSB compared with RIP was evaluated using an intra-class correlation coefficient. Results: Mean fentanyl dose was 629 µg. A statistically significant association was found between the RIP and SCSB data in the manual SCSB analysis (P |
| Databáze: | OpenAIRE |
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