Seroprevalence of antibodies to tick-borne encephalitis virus and Anaplasma phagocytophilum in healthy adults from western Norway
| Autor: | Reidar Hjetland, Susanne Gjeruldsen Dudman, Elling Ulvestad, Nils Grude, Anna J. Henningsson, Kirsti Vainio |
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| Rok vydání: | 2014 |
| Předmět: |
Adult
Male Microbiology (medical) Endemic Diseases Human granulocytic anaplasmosis Population Blood Donors Antibodies Viral Virus Encephalitis Viruses Tick-Borne Young Adult Seroepidemiologic Studies Humans Medicine Seroprevalence education Aged education.field_of_study seroprevalence General Immunology and Microbiology biology Norway business.industry Ehrlichiosis General Medicine Middle Aged bacterial infections and mycoses medicine.disease biology.organism_classification Antibodies Bacterial Virology Anaplasma phagocytophilum Titer Tick-borne encephalitis virus Infectious Diseases Immunoglobulin G Immunology blood donors Female business Encephalitis Tick-Borne Encephalitis |
| Zdroj: | Infectious Diseases |
| ISSN: | 2374-4243 2374-4235 |
| DOI: | 10.3109/00365548.2014.959044 |
| Popis: | The aim of this study was to assess the seroprevalence of antibodies to tick-borne encephalitis virus (TBEV) and Anaplasma phagocytophilum in a healthy adult population from Sogn and Fjordane county in western Norway. Sera from 1, 213 blood donors were analysed for IgG-antibodies to TBEV, and a random subgroup of 301 donors for IgG to A. phagocytophilum. In the TBEV ELISA, five (0.4%) sera were positive. These were all interpreted as “false” positives, as four had received vaccines against flaviviruses, and the remaining was negative for neutralizing antibodies to TBEV. Antibodies to A. phagocytophilum were detected by indirect immunofluorescence in 49 (16.2%) subjects (titer range 80-1280). The results indicate that TBE currently is not endemic in this part of western Norway. However, there is serological evidence of the existence of human granulocytic anaplasmosis in the population. acceptedVersion |
| Databáze: | OpenAIRE |
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