Fiber-Optic Raman Spectrum Sensor for Fast Diagnosis of Esophageal Cancer
| Autor: | Zhuoyue Li, Xiu He, Jianhua Dai, Kang Li, Zengling Ran, Dian-chun Fang, Guiyong Peng, Xiang Zou, Yao Chen, Tingting Yang, Lijian Yin |
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| Rok vydání: | 2018 |
| Předmět: |
lcsh:Applied optics. Photonics
Optical fiber Materials science Focus (geometry) Frequency band 02 engineering and technology 01 natural sciences Signal law.invention 010309 optics symbols.namesake 020210 optoelectronics & photonics law 0103 physical sciences 0202 electrical engineering electronic engineering information engineering esophageal cancer Raman spectrum business.industry lcsh:TA1501-1820 Fiber-optic Laser Atomic and Molecular Physics and Optics Electronic Optical and Magnetic Materials Lens (optics) symbols Optoelectronics business Raman spectroscopy Energy (signal processing) |
| Zdroj: | Photonic Sensors, Vol 9, Iss 1, Pp 53-59 (2018) |
| ISSN: | 2190-7439 1674-9251 |
| DOI: | 10.1007/s13320-018-0516-7 |
| Popis: | A fiber-optic Raman spectrum sensor system is used for the fast diagnosis of esophageal cancer during clinical endoscopic examination. The system contains a 785 nm exciting laser, a Raman fiber-optic probe with 7 large core fibers and a focus lens, and a highly sensitive spectrum meter. The Raman spectrum of the tissue could be obtained within 1 second by using such a system. A signal baseline removal and denoising technology is used to improve the signal quality. A novel signal feature extraction method for differentiating the normal and esophageal cancer tissues is proposed, based on the differences in half-height width (HHW) in 1200 cm‒1 to 1400 cm‒1 frequency band and the ratios of the spectral integral energy between 1600 cm‒1 − 1700 cm‒1 and 1500 cm‒1 − 1600 cm‒1 band. It shows a high specificity and effectivity for the diagnosis of esophageal cancer. |
| Databáze: | OpenAIRE |
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