Levels of Insulin-Like Growth Factor I in Full- and Preterm Human Milk in Comparison to Levels in Cow’s Milk and in Milk Formulas
| Autor: | Takayosi Kuroume, Ken Itoh, Kanji Nagashima |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Birth weight Gestational Age Insulin-like growth factor fluids and secretions Animal science Pregnancy Internal medicine medicine Animals Birth Weight Humans Insulin-Like Growth Factor I Infant Nutritional Physiological Phenomena Post partum Milk Human business.industry Infant Newborn food and beverages Gestational age Radioimmunoassay medicine.disease Somatomedin Milk Endocrinology Pediatrics Perinatology and Child Health Female Infant Food business Developmental Biology Hormone |
| Zdroj: | Neonatology. 58:343-346 |
| ISSN: | 1661-7819 1661-7800 |
| Popis: | The content of insulin-like growth factor I (IGF-I) in human milk, cow’s milk and cow’s-milk-based infnat formulas was determined by radioimmunoassay. The mean levels of IGF-I in full-term milk and preterm milk 0–4 days post partum 2.2 ± 0.3 and 2.4 ± 0.5 ng/mg protein, respectively. The IGF-I content in human milk was not affected by gestational age or birth weight and was constantly excreted up to 10 days post partum. The IGF-I content in human milk was significantly higher than that in cow’s milk (0.6 ± 0.1 ng/ mg protein, p < 0.01). IGF-I was not detected in the milk formulas. The IGF-I in human milk might be absorbed or could act locally in the intestine and may be of importance in the nutrition of neonates. |
| Databáze: | OpenAIRE |
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