Left Ventricular Regional Wall Motion Abnormality in the Setting of Acute Loperamide Overdose
| Autor: | Timonthy Montrief, Kasha Bornstein, Mehruba Anwar Parris |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Cardiotoxicity
Loperamide Loperamide overdose business.industry lcsh:Medical emergencies. Critical care. Intensive care. First aid Case Report lcsh:RC86-88.9 Antidiarrheal Agent Cardiac dysrhythmia 030204 cardiovascular system & hematology Emergency Nursing Food and drug administration 03 medical and health sciences 0302 clinical medicine Opioid Anesthesia Emergency Medicine Medicine 030212 general & internal medicine Wall motion business medicine.drug |
| Zdroj: | Clinical Practice and Cases in Emergency Medicine, Vol 3, Iss 3 (2019) Bornstein, Kasha; Montrief, Timonthy; & Anwar Parris, Mehruba. (2019). Left Ventricular Regional Wall Motion Abnormality in the Setting of Acute Loperamide Overdose. Clinical Practice and Cases in Emergency Medicine, Advance online publication. Retrieved from: http://www.escholarship.org/uc/item/9hm8j0jn Clinical Practice and Cases in Emergency Medicine |
| ISSN: | 2474-252X |
| Popis: | Loperamide is an inexpensive, over-the-counter antidiarrheal agent with emerging reports of overdose due to its opioid properties. Although it is considered by many patients to be safe, cardiotoxicity has been reported, prompting the United States Food and Drug Administration to release a warning regarding the arrhythmogenic potential of loperamide. We present a case of a 32-year-old male presenting in acute loperamide overdose and subsequent cardiac dysrhythmia with focal wall motion abnormalities on echocardiogram. This finding has not been previously reported in the literature and is unique in this clinical presentation. We also highlight the potential mechanisms for loperamide cardiotoxicity and its challenging management. |
| Databáze: | OpenAIRE |
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