A Case of Post-Streptococcal Glomerulonephritis with Diffuse Alveolar Hemorrhage
| Autor: | Chang Hoon Lim, Byung Kee Bang, Yoon Sik Chang, Mi Jung Shin, Ho Chul Song, Suk Young Kim, Byung Soo Kim, Euy Jin Choi, Hye Young Sung, Young Ok Kim |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2007 |
| Předmět: |
Lung Diseases
Pathology medicine.medical_specialty Biopsy Renal function Hemorrhage Case Report Post-Streptococcal Glomerulonephritis Kidney urologic and male genital diseases Glomerulonephritis Oliguria Streptococcal Infections Correspondence medicine Humans Respiratory distress medicine.diagnostic_test business.industry Diffuse alveolar hemorrhage General Medicine Middle Aged medicine.disease Pharyngitis Diffuse Alveolar Hemorrhage Pulmonary Alveoli medicine.anatomical_structure Female Renal biopsy medicine.symptom business |
| Zdroj: | Journal of Korean Medical Science |
| ISSN: | 1598-6357 1011-8934 |
| Popis: | Acute post-streptococcal glomerulonephritis (PSGN) is characterized by an abrupt onset of edema, hypertension, and hematuria. Life-threatening diffuse alveolar hemorrhage (DAH) is rarely associated with acute PSGN. There have been only two reported cases worldwide, and no case has been reported previously in Korea. Here, we present a patient who clinically presented with pulmonary-renal syndrome; the renal histology revealed post-infectious glomerulonephritis of immune complex origin. A 59-yr-old woman was admitted with oliguria and hemoptysis two weeks after pharyngitis. Renal insufficiency rapidly progressed, and respiratory distress developed. Chest radiography showed acute progressive bilateral pulmonary infiltrates. The clinical presentation suggested DAH with PSGN. Three days after treatment with high-dose steroids, the respiratory distress and pulmonary infiltrates resolved. Electron microscopy of a renal biopsy specimen sample revealed diffuse proliferative glomerulonephritis with characteristic subendothelial deposits of immune complex (''hump''). The renal function of the patient was restored, and the serum creatinine level was normalized after treatment. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|