Circadian variation in human cerebrospinal fluid production measured by magnetic resonance imaging
| Autor: | Freddy Ståhlberg, Ole Henriksen, M Herning, Christer Owman, Carsten Thomsen, Christer Nilsson |
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| Rok vydání: | 1992 |
| Předmět: |
Adult
Male Measurement method medicine.diagnostic_test Physiology Chemistry business.industry Magnetic resonance imaging Magnetic Resonance Imaging Circadian Rhythm Normal volunteers Cerebrospinal fluid Physiology (medical) Cerebral aqueduct Calibration medicine Humans Regression Analysis Female Intraindividual comparison Circadian rhythm Nuclear medicine business Cerebrospinal Fluid |
| Zdroj: | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 262:R20-R24 |
| ISSN: | 1522-1490 0363-6119 |
| DOI: | 10.1152/ajpregu.1992.262.1.r20 |
| Popis: | Recent advances in magnetic resonance imaging have made it possible to visualize and quantify flow of cerebrospinal fluid (CSF) in the brain. The net flow of CSF through the cerebral aqueduct was used to measure CSF production in six normal volunteers at different times during a 24-h period. CSF production varied greatly both intra- and interindividually. The average CSF production in each time interval showed a clear tendency to circadian variation, with a minimum production 30% of maximum values (12 +/- 7 ml/h) approximately 1800 h and a nightly peak production approximately 0200 h of 42 +/- 2 ml/h. The total CSF production during the whole 24-h period, calculated as an average of all measurements, was 650 ml for the whole group and 630 ml for repeated measurements in each time interval in one of the volunteers. |
| Databáze: | OpenAIRE |
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