Atrial fibrillation burden, episode duration and frequency in relation to quality of life in patients with implantable cardiac monitor
| Autor: | Steen M. Jensen, Carina Blomström-Lundqvist, Elena Sciaraffia, Aigars Rubulis, Pekka Raatikainen, Victoria Jansson, Lennart Bergfeldt, Jonas Schwieler, Göran Kennebäck |
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| Přispěvatelé: | HUS Heart and Lung Center, Kardiologian yksikkö |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
IMPACT Health-related quality of life Randomized macromolecular substances 030204 cardiovascular system & hematology Vitality 03 medical and health sciences Loop recorder 0302 clinical medicine Pharmacotherapy Quality of life Internal medicine Heart rate ABLATION Diseases of the circulatory (Cardiovascular) system Medicine In patient Cardiac and Cardiovascular Systems cardiovascular diseases 030212 general & internal medicine Original Paper Kardiologi business.industry Atrial fibrillation Implantable cardiac monitor medicine.disease Confidence interval 3. Good health Atrial fibrillation burden Quartile RC666-701 3121 General medicine internal medicine and other clinical medicine cardiovascular system Cardiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | International Journal of Cardiology: Heart & Vasculature, Vol 34, Iss, Pp 100791-(2021) International Journal of Cardiology. Heart & Vasculature |
| Popis: | Highlights • Assessing the relationship between atrial fibrillation and quality of life. • Implantable loop recorders assessed rhythm continuously in symptomatic patients. • Atrial fibrillation burden, episode duration and frequency were included. • Higher atrial fibrillation burden was associated with impaired quality of life. Aims To assess the relation between atrial fibrillation (AF) characteristics and health-related quality of life (QoL), and which AF characteristic had the greatest impact. Method The AF characteristics burden (percentage of time in AF), duration and number of AF episodes/month were obtained from implantable cardiac monitors during the 2-month run-in period in 150 patients included in the randomized CAPTAF trial comparing early ablation and antiarrhythmic drug therapy. The QoL was measured by the General Health and Vitality dimensions of the 36-Item Short-Form Health Survey. AF characteristics were analysed continuously and in quartiles (Q1-Q4). Results Greater AF burden (p = 0.003) and longer AF episodes (p = 0.013) were associated with impaired QoL (Vitality score only) in simple linear regression analyses. Greater AF burden was, however, the only AF characteristic associated with lower QoL, when adjusted for sex, type of AF, hypertension, heart rate above 110 beats per minute during AF, and beta-blocker use in multiple linear regression analyses. For every 10% increase in AF burden there was a 1.34-point decrease of Vitality score (95% confidence interval (CI) −2.67 to −0.02, p = 0.047). The Vitality score was 12 points lower (95% CI −22.73 to −1.27, p = 0.03) in patients with an AF burden > 33% (Q4) versus those with |
| Databáze: | OpenAIRE |
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