Koniamborine, the First Pyrano[3,2-b]indole Alkaloid and Other Secondary Metabolites from Boronella koniambiensis

Autor: Raphaël Grougnet, Sofia Mitaku, Alexios-Leandros Skaltsounis, Marc Litaudon, Francois Tillequin, Prokopios Magiatis, Thierry Sévenet, Nikolas Fokialakis
Rok vydání: 2005
Předmět:
Zdroj: Journal of Natural Products. 68:1083-1086
ISSN: 1520-6025
0163-3864
DOI: 10.1021/np050013w
Popis: Two new alkaloids, (-)-cis-1,2-dihydroxy-1,2-dihydromedicosmine (3) and koniamborine (4), have been isolated from Boronella koniambiensis aerial parts. Their structures have been established from NMR and mass data. Koniamborine is a novel type of alkaloid, which derives from the pyrano[3,2-b]indole basic skeleton, described for the first time from nature. 6-Methoxy-1-methylisatin, also present in the plant material, can be considered biogenetically as a degradation product of the fused pyrone ring of 4.
Databáze: OpenAIRE