Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440
| Autor: | A. Düsterhöft, Jonathan A. Eisen, Daniel S. Kosack, Robert J. Dodson, A. Moazzez, V. A. P. Martins Dos Santos, Claire M. Fraser, H. Hilbert, Jeremy Peterson, J. Lauber, Kevin Tran, H. Wedler, Maureen J. Beanan, Owen White, D. Moestl, Jörg D. Hoheisel, Ramana Madupu, Sean C. Daugherty, C. Kiewitz, Mark A. Holmes, Robert T. DeBoy, P. Chris Lee, Erik Holtzapple, Hoda Khouri, Burkhard Tümmler, Diana Stjepandic, David J. Scanlan, Lauren M. Brinkac, Derrick E. Fouts, K. Lee, Ioana R. Hance, Mihai Pop, Christian Weinel, William C. Nelson, M. Rizzo, Steven R. Gill, Ian T. Paulsen, James F. Kolonay, Kenneth N. Timmis, T. Utterback, Sabina Heim, Karen E. Nelson, M. Straetz |
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| Rok vydání: | 2003 |
| Předmět: |
Sequence analysis
Molecular Sequence Data Virulence Computational biology medicine.disease_cause Microbiology Genome Open Reading Frames Microbial ecology Bacterial Proteins medicine Life Science Pseudomonas exotoxin Gene Ecology Evolution Behavior and Systematics Phylogeny Genetics Whole genome sequencing biology Base Sequence Pseudomonas aeruginosa Pseudomonas putida biology.organism_classification Genes Bacterial Energy Metabolism Genome Bacterial |
| Zdroj: | Environmental Microbiology 4 (2002) 12 Environmental Microbiology, 4(12), 799-808 |
| ISSN: | 1462-2912 |
| Popis: | Pseudomonas putida is a metabolically versatile saprophytic soil bacterium that has been certified as a biosafety host for the cloning of foreign genes. The bacterium also has considerable potential for biotechnological applications. Sequence analysis of the 6.18 Mb genome of strain KT2440 reveals diverse transport and metabolic systems. Although there is a high level of genome conservation with the pathogenic Pseudomonad Pseudomonas aeruginosa (85% of the predicted coding regions are shared), key virulence factors including exotoxin A and type III secretion systems are absent. Analysis of the genome gives insight into the non-pathogenic nature of P. putida and points to potential new applications in agriculture, biocatalysis, bioremediation and bioplastic production. |
| Databáze: | OpenAIRE |
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