Ipsilateral cerebral atrophy with thalamic tumor of childhood

Autor: Jiro Suzuki, Shunichi Saso, Ryungchan Kwak
Rok vydání: 1978
Předmět:
Zdroj: Journal of Neurosurgery. 48:443-449
ISSN: 0022-3085
DOI: 10.3171/jns.1978.48.3.0443
Popis: ✓ A case of cerebral tumor with ipsilateral cerebral hemiatrophy is presented and five previously reported cases are reviewed. The etiology of this entity is discussed on the basis of the symptomatological and clinicopathological findings noted in these six cases. It is suggested that ipsilateral cerebral hemiatrophy is due to thinning of the cerebral cortex with degeneration and disappearance of ganglion cells, demyelination in the subcortex, and destruction of axons. The mechanism proposed for ipsilateral cerebral hemiatrophy due to thalamic tumor is that thalamic tumor causes degeneration and disappearance of thalamic ganglion cells and nerve fibers, with consequent secondary Wallerian degeneration of afferent and projecting fibers from the thalamus as well as retrograde degeneration of efferent fibers, thus resulting in extensive atrophy of the cerebral cortex and subcortical tissue.
Databáze: OpenAIRE