Heterozygous loss of Dip2B enhances tumor growth and metastasis by altering immune microenvironment

Autor:	Salah, Adlat, Farooq, Hayel, Yang, Chen, Rajiv Kumar, Sah, Zin, Mar Oo, Mahmoud, Al-Azab, May, Zun Zaw Myint, Noor, Bahadar, Fatoumata, Binta Bah, Nasser, Mi, Mohammed, Safi, Xuechao, Feng, Ping, Zhu, Yaowu, Zheng
Rok vydání:	2022
Předmět:	Mice Knockout Pharmacology Mice Cell Line Tumor Macrophages Neoplasms Immunology Tumor Microenvironment Animals Immunology and Allergy Nerve Tissue Proteins Neoplasm Metastasis Cell Proliferation
Zdroj:	International Immunopharmacology. 105:108559
ISSN:	1567-5769
DOI:	10.1016/j.intimp.2022.108559
Popis:	Cancer is caused by abnormal cell growth and metastasis to other tissues. Development of cancers is complex and underlining mechanisms are mostly unknown. Disco-interacting protein 2 homolog B (DIP2B) is a member of Dip2. There have been reports suggesting that Dip2B may participate in tumor growth and development. However, direct link between DIP2B and cancer development is missing. In this study, Dip2b
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9fc32d7ee83b03a01adc7cc9dc92c0 https://doi.org/10.1016/j.intimp.2022.108559 Zobrazit plný text záznamu Full Text from ScienceDirect