Successful treatment of meningococcal bacteremia using oral doxycycline: A case report
| Autor: | Benjamin Davido, Morgan Matt, Latifa Noussair, Aurélien Dinh, S. Simeon, S. Berbescu, L. Armand-Lefevre |
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| Přispěvatelé: | Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), University of Medicine and Pharmacy 'Carol Davila' Bucharest (UMPCD), AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Université Paris Diderot - Paris 7 (UPD7) |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Serotype medicine.medical_specialty 030106 microbiology Tick medicine.disease_cause 03 medical and health sciences 0302 clinical medicine [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases medicine 030212 general & internal medicine Meningococcal bacteremia Doxycycline Purpura fulminans biology business.industry Neisseria meningitidis General Medicine medicine.disease biology.organism_classification Dermatology 3. Good health Infectious Diseases Bacteremia [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology Headaches medicine.symptom business Staphylococcus medicine.drug |
| Zdroj: | International Journal of Infectious Diseases International Journal of Infectious Diseases, Elsevier, 2020, 92, pp.78-80. ⟨10.1016/j.ijid.2019.12.032⟩ |
| ISSN: | 1201-9712 1878-3511 |
| Popis: | International audience; We report the case of an 18-year-old immunocompetent man who presented to the hospital with fever, headaches, and arthromyalgia, which progressed to include an erythematous rash. He had a history of a tick bite 72 h earlier. The diagnosis of rickettsial infection was suspected and a course of doxycycline was initiated for a total of 5 days. His evolution was rapidly favorable under treatment, with resolution of the symptoms within 24 h. Blood cultures came back positive for Neisseria meningitidis serotype B, indicating an authentic purpura fulminans. Purpura fulminans is a medical emergency, a syndrome of intravascular thrombosis characterized by a very rapid evolution that requires early recognition and specific treatment. It is commonly described in the young and healthy patient and has high mortality and morbidity. Common bacteria mainly associated with purpura fulminans are Meningococcus spp., Pneumococcus spp., and Staphylococcus spp. |
| Databáze: | OpenAIRE |
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