Regorafenib enhances anti-PD1 immunotherapy efficacy in murine colorectal cancers and their combination prevents tumor regrowth

Autor:	Susanne Koletnik, Dennis Doleschel, Fabian Kiessling, Anne Rix, Wiltrud Lederle, Dieter Zopf, Sabine Hoff
Přispěvatelé:	Publica
Jazyk:	angličtina
Rok vydání:	2021
Předmět:	Cancer Research Combination therapy Colorectal cancer Pyridines medicine.medical_treatment Programmed Cell Death 1 Receptor Macrophage polarization Metastasis chemistry.chemical_compound Mice Regorafenib Cell Line Tumor Medicine Animals Humans RC254-282 Tumor microenvironment business.industry Research Phenylurea Compounds Neoplasms. Tumors. Oncology. Including cancer and carcinogens Drug Synergism Immunotherapy medicine.disease Preclinical Oncology chemistry Apoptosis Cancer research Anti-PD1 antibody business Colorectal Neoplasms
Zdroj:	Journal of Experimental & Clinical Cancer Research : CR Journal of experimental & clinical cancer research 40(1), 288 (2021). doi:10.1186/s13046-021-02043-0 Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-14 (2021)
ISSN:	1756-9966 0392-9078
Popis:	Journal of experimental & clinical cancer research 40(1), 288 (2021). doi:10.1186/s13046-021-02043-0 Published by Springer, Berlin ; Heidelberg
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab98cf9179bb969a3e3b7319e8b77865 http://europepmc.org/articles/PMC8436536 Zobrazit plný text záznamu Full text from SpringerLink