Functional optical coherence tomography at altitude: retinal microvascular perfusion and retinal thickness at 3,800 meters

Autor:	Jacquie Baker, Mohammad A. Safarzadeh, Anthony V. Incognito, Nicholas G. Jendzjowsky, Glen E. Foster, Jordan D. Bird, Satish R. Raj, Trevor A. Day, Caroline A. Rickards, Natalia Zubieta-DeUrioste, Usman Alim, Richard J. A. Wilson
Rok vydání:	2022
Předmět:	Male Perfusion Physiology Physiology (medical) Altitude Critical Illness Humans Female Altitude Sickness Hypoxia Brain Retina Tomography Optical Coherence
Zdroj:	Journal of applied physiology (Bethesda, Md. : 1985). 133(3)
ISSN:	1522-1601
Popis:	Measuring the retinal microvasculature at high altitude provides a surrogate for cerebral microvasculature, offering potential insight into consequence of cerebral hypoxia in critical illness. This study demonstrates dynamic regulation of the retina during rapid ascent and prolonged exposure to high altitude and is the first to demonstrate sex-specific differences in retinal microvasculature at high altitude. The ability to dynamically assess intact microvasculature contiguous with the brain has widespread research and clinical applications.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab8e0f06fb6ec60c83d754b7370c4724 https://pubmed.ncbi.nlm.nih.gov/35771223 Zobrazit plný text záznamu