Is High Definition MLC Dosimetrically Superior to Standard Definition MLC for SIB-SBRT for Carcinoma Prostate
Autor: | Pichandi A, K M Ganesh, Bijina T K |
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Rok vydání: | 2019 |
Předmět: |
Male
Organs at Risk 0301 basic medicine Carcinoma prostate Irradiated Volume VMAT Radiosurgery 03 medical and health sciences 0302 clinical medicine Standard definition Prostate Image Processing Computer-Assisted medicine Humans IMRT Radiometry Retrospective Studies SBRT business.industry Radiotherapy Planning Computer-Assisted SIB Prostatic Neoplasms Radiotherapy Dosage General Medicine Patient specific Prognosis 030104 developmental biology medicine.anatomical_structure 030220 oncology & carcinogenesis High definition Radiotherapy Intensity-Modulated Particle Accelerators Tomography X-Ray Computed Nuclear medicine business Research Article MLC |
Zdroj: | Asian Pacific Journal of Cancer Prevention : APJCP |
ISSN: | 2476-762X |
Popis: | Objective: The study was conducted to quantitatively evaluate the dosimetric effects of high definition (2.5 mm) and standard definition (5.0 mm) MLC on the quality of SBRT plans using SIB-IMRT and SIB-VMAT technique for carcinoma prostate and also to evaluate the dosimetric advantage of one technique over the other. Materials and Methods: Seventeen annonymized planning CT data sets were used to generate plans for both VMAT and IMRT techniques using 2.5 mm and 5.0 mm MLC.The prescription to the nodule was 45Gy in 5 fractions and to the prostate was 35Gy in 5 fractions.CI, GI, D2%, D98%, D50% and V95% for target; D2%, Dmean, V80%, V20% for OAR’s; V5% of the irradiated volume, and delivered MU’s were analyzed.An independent t-test was used to compare the plans. Patient specific QA for all plans were also performed and analyzed. Results: Minor difference in dosimetric indices was observed between 2.5mm and 5mm MLC VMAT plans, except D2% (PTV35) and D98% (GTV45) were better in 2.5mm MLC plans (p |
Databáze: | OpenAIRE |
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