Adenoid cystic salivary gland carcinoma: treatment with irradiation and surgery
| Autor: | Joseph R. Simpson, S E Thawley, H M Matsuba |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Adult
Male medicine.medical_specialty Adenoid cystic carcinoma medicine.medical_treatment Adenoid medicine Carcinoma Humans Combined Modality Therapy Radiology Nuclear Medicine and imaging Respiratory system Lymph node Aged Lung business.industry Middle Aged Salivary Gland Neoplasms medicine.disease Carcinoma Adenoid Cystic Surgery Radiation therapy medicine.anatomical_structure Lymphatic Metastasis Female Neoplasm Recurrence Local business |
| Zdroj: | Radiology. 151:509-512 |
| ISSN: | 1527-1315 0033-8419 |
| DOI: | 10.1148/radiology.151.2.6324280 |
| Popis: | The records of 71 patients with adenoid cystic carcinoma of the salivary glands were reviewed to determine the dose response relationships for this aggressive tumor. Local control after treatment was determined for all patients and analyzed with respect to extent of surgery and dose of radiation. Of 70 patients who were available for evaluation of local control, 28 (40%) had a local recurrence and 42 (60%) did not. The highest control rates were found in patients who underwent both radiation therapy and surgery. Patients who received a dose equal to or greater than 6,000 rad (60 Gy) in addition to surgery had significantly higher local control rates than those who received less than 6,000 rad (60 Gy). Distant metastases developed in 50% of patients regardless of local control, with the following distribution: 39% lung, 19% bone, and 10% disseminated soft-tissue metastases. Lymph node involvement was rare. Implications for combined modality treatment are discussed. |
| Databáze: | OpenAIRE |
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